Emergency Medicine Pulmonary Embolism Testing Multicentre Study

Status: Recruiting
Location: See location...
Intervention Type: Diagnostic test
Study Type: Observational
SUMMARY

It is important to diagnose pulmonary embolism in a timely manner to prevent death and long-term disability. More than half a million people (4-5% of emergency department patients) are tested for pulmonary embolism, although the positive rate is low. Imaging for PE testing exposes patients to radiation, is expensive, adds time to the emergency visit, and can lead to a false positive diagnoses. Existing protocols aimed at reducing unnecessary pulmonary embolism imaging are complex and seldom used by emergency physicians. Too many patients undergo unnecessary pulmonary embolism imaging. A new tool (called Adjust-Unlikely) could safely reduce pulmonary embolism imaging in Canada. A research group composed of researchers, emergency physicians, and patients developed the Adjust-Unlikely clinical decision rule: a rule which has been customized for emergency physicians and emergency patients. Adjust-Unlikely is highly sensitive at the bedside, meaning there are very few false negative results. The study aim is to prospectively validate Adjust-Unlikely pulmonary embolism testing in emergency patients with suspected pulmonary embolism.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Emergency department patient who is tested by an emergency physician for PE

Locations
Other Locations
Canada
Kingston Health Sciences Centre
RECRUITING
Kingston
Contact Information
Primary
Natasha S Clayton, CRA, RA
natasha.clayton@queensu.ca
4165663590
Time Frame
Start Date: 2024-01-01
Estimated Completion Date: 2027-09-30
Participants
Target number of participants: 4000
Treatments
Emergency department patients tested for pulmonary embolism.
Related Therapeutic Areas
Sponsors
Collaborators: Canadian Institutes of Health Research (CIHR)
Leads: Dr. Kerstin de Wit

This content was sourced from clinicaltrials.gov